| Name |
Secondary polycythaemia (2ry_polycythaemia) |
| Category |
Haematological or immunological |
| Sex |
|
| Adult |
Yes |
| UUID |
ae441f83-cf86-476a-8206-60f7a867c227 |
| Definition |
Abnormally high mass or concentration of red blood cells in the blood, either due to an increase in erythropoiesis or a decrease in plasma volume. |
Ontologies
Key Summary Statistics
Cases from any source
| Total |
817 |
| Female (%) |
257 (31%) |
| Male (%) |
560 (69%) |
Year first recorded
Cases linked in all UK Biobank sources
Cross-source concordance
Vertical bars correspond to number of cases per source/intersection; horizontal bars to left correspond to total number of cases per source.
Incidence & prevalence
Baseline prevalence stratified by sex
| Female |
2.48 (1.42,3.53) |
| Male |
6.44 (4.58,8.3) |
Incidence stratified by sex
| Female |
0.4 (0.24,0.57) |
| Male |
0.97 (0.69,1.25) |
Incidence stratified by age
| Ages 40-44 |
0.4 (0.01,0.8) |
| Ages 45-49 |
0.52 (0.13,0.9) |
| Ages 50-54 |
0.57 (0.2,0.94) |
| Ages 55-59 |
0.52 (0.2,0.84) |
| Ages 60-64 |
0.69 (0.37,1.01) |
| Ages 65-69 |
1.05 (0.6,1.51) |
Period prevalence
Methods
Comparison with general population
Sex-standardised prevalence from CALIBER study (Kuan et al. 2019)
| Population |
Ages 40-49 |
Ages 50-59 |
Ages 60-69 |
| UK Biobank |
7 (4,10) |
9 (7,12) |
12 (9,14) |
| CALIBER |
9 (8,10) |
16 (15,17) |
22 (20,23) |
Stratified by age and Townsend deprivation status
| Deprivation status |
Ages 40-49 |
Ages 50-59 |
Ages 60-69 |
| Least deprived |
6(2,14) |
8(4,15) |
9(5,14) |
| Low |
4(1,13) |
7(3,13) |
13(9,20) |
| Medium |
6(2,14) |
9(5,16) |
8(4,13) |
| High |
4(1,12) |
6(3,12) |
11(7,18) |
| Most deprived |
12(6,21) |
15(9,24) |
17(12,25) |
Stratified by age and country
| Country |
Ages 40-49 |
Ages 50-59 |
Ages 60-69 |
| England |
6(4,10) |
8(6,11) |
11(9,14) |
| Scotland |
2(0,13) |
7(2,15) |
10(5,19) |
| Wales |
20(7,44) |
25(13,44) |
22(12,36) |
Definition
| UK Biobank field id |
Description |
Code |
Value |
| 41202 |
Diagnoses - main ICD10 |
D75.1 |
Secondary polycythaemia |
| 41204 |
Diagnoses - secondary ICD10 |
D75.1 |
Secondary polycythaemia |
| 40001 |
Underlying (primary) cause of death: ICD10 |
D75.1 |
Secondary polycythaemia |
| 40002 |
Contributory (secondary) causes of death: ICD10 |
D75.1 |
Secondary polycythaemia |
| 42040 |
GP clinical event records |
D410000 |
Stress polycythaemia |
| 42040 |
GP clinical event records |
D410011 |
Spurious polycythaemia |
| 42040 |
GP clinical event records |
D410100 |
High altitude polycythaemia |
| 42040 |
GP clinical event records |
D410200 |
Polycythaemia due to cyanotic heart disease |
| 42040 |
GP clinical event records |
D410300 |
Polycythaemia due to cyanotic respiratory disease |
| 42040 |
GP clinical event records |
D410400 |
Renal polycythaemia |
| 42040 |
GP clinical event records |
D410.00 |
Secondary polycythaemia |
| 42040 |
GP clinical event records |
D410z00 |
Secondary polycythaemia NOS |