| Name |
Ankylosing spondylitis (ank_spond) |
| Category |
Musculoskeletal |
| Sex |
|
| Adult |
Yes |
| UUID |
f969d03e-0f21-44e4-85e3-b30a0e5ea54f |
| Definition |
A bone inflammation disease that results in inflammation in the joints of the spine and pelvis |
Ontologies
Key Summary Statistics
Cases from any source
| Total |
2245 |
| Female (%) |
885 (39%) |
| Male (%) |
1360 (61%) |
Year first recorded
Cases linked in all UK Biobank sources
Cross-source concordance
Vertical bars correspond to number of cases per source/intersection; horizontal bars to left correspond to total number of cases per source.
Incidence & prevalence
Baseline prevalence stratified by sex
| Female |
27.58 (24.05,31.11) |
| Male |
56.84 (51.32,62.35) |
Incidence stratified by sex
| Female |
0.63 (0.43,0.84) |
| Male |
0.87 (0.6,1.13) |
Incidence stratified by age
| Ages 40-44 |
0.4 (0.01,0.8) |
| Ages 45-49 |
0.37 (0.05,0.7) |
| Ages 50-54 |
0.7 (0.29,1.11) |
| Ages 55-59 |
0.94 (0.51,1.37) |
| Ages 60-64 |
0.77 (0.43,1.11) |
| Ages 65-69 |
0.96 (0.53,1.39) |
Period prevalence
Methods
Comparison with general population
Sex-standardised prevalence from CALIBER study (Kuan et al. 2019)
| Population |
Ages 40-49 |
Ages 50-59 |
Ages 60-69 |
| UK Biobank |
27 (22,32) |
35 (30,40) |
38 (34,43) |
| CALIBER |
22 (21,24) |
30 (28,31) |
38 (36,40) |
Stratified by age and Townsend deprivation status
| Deprivation status |
Ages 40-49 |
Ages 50-59 |
Ages 60-69 |
| Least deprived |
16(8,28) |
38(27,50) |
44(35,55) |
| Low |
24(14,39) |
33(23,45) |
41(32,51) |
| Medium |
21(11,34) |
30(21,41) |
35(27,44) |
| High |
36(25,51) |
34(25,46) |
30(22,39) |
| Most deprived |
32(22,45) |
39(29,51) |
42(32,53) |
Stratified by age and country
| Country |
Ages 40-49 |
Ages 50-59 |
Ages 60-69 |
| England |
27(22,34) |
35(30,41) |
39(34,44) |
| Scotland |
20(10,37) |
31(20,45) |
33(22,46) |
| Wales |
28(12,56) |
39(23,61) |
42(28,60) |
Definition
| UK Biobank field id |
Description |
Code |
Value |
| 20002 |
Non-cancer illness code, self-reported |
1313 |
ankylosing spondylitis |
| 41202 |
Diagnoses - main ICD10 |
M45 |
Ankylosing spondylitis |
| 41204 |
Diagnoses - secondary ICD10 |
M45 |
Ankylosing spondylitis |
| 40001 |
Underlying (primary) cause of death: ICD10 |
M45 |
Ankylosing spondylitis |
| 40002 |
Contributory (secondary) causes of death: ICD10 |
M45 |
Ankylosing spondylitis |
| 42040 |
GP clinical event records |
2377.00 |
O/E - ankyl.spondyl.chest def. |
| 42040 |
GP clinical event records |
388p.00 |
BASDAI - Bath ankylosing spondylitis disease activity index |
| 42040 |
GP clinical event records |
N100.00 |
Ankylosing spondylitis |
| 42040 |
GP clinical event records |
N100.11 |
Marie - Strumpell spondylitis |