Metadata

Name Asbestosis (asbestosis)
Category Respiratory
Sex
Adult Yes
UUID e6fa1fbb-5101-4ad5-854b-84b4d8dcd754
Definition A pneumoconiosis caused by inhalation and retention of asbestos fibers.

Ontologies

Disease Ontology (DOID) DOID_10320
MeSH D001195
SNOMED-CT 22607003
FinnGen J10_ASBESTPNEUMOC

Key Summary Statistics

Cases from any source

Total 764
Female (%) 30 (4%)
Male (%) 734 (96%)

Year first recorded

asbestosis year of first event

Cases linked in all UK Biobank sources

Cross-source concordance

Vertical bars correspond to number of cases per source/intersection; horizontal bars to left correspond to total number of cases per source.

Cross-sourced asbestosis cases

Incidence & prevalence

Sex and age-stratified incidence and prevalence of asbestosis

Baseline prevalence stratified by sex

Female 0.12 (-0.11,0.35)
Male 12.46 (9.87,15.05)

Incidence stratified by sex

Female 0.05 (-0.01,0.11)
Male 1.31 (0.98,1.63)

Incidence stratified by age

Ages 40-44 0.0 (0.0,0.0)
Ages 45-49 0.07 (-0.07,0.22)
Ages 50-54 0.06 (-0.06,0.19)
Ages 55-59 0.42 (0.13,0.7)
Ages 60-64 0.46 (0.2,0.72)
Ages 65-69 2.16 (1.52,2.81)

Period prevalence

Methods

Comparison with general population

Sex-standardised prevalence from CALIBER study (Kuan et al. 2019)

CALIBER and UKB asbestosis prevalence comparison for multiple age groups

Population Ages 40-49 Ages 50-59 Ages 60-69
UK Biobank 0 (0,1) 2 (1,4) 15 (13,18)
CALIBER 4 (4,5) 25 (24,27)

Stratified by age and Townsend deprivation status

Deprivation status Ages 40-49 Ages 50-59 Ages 60-69
Least deprived 0(NaN,NaN) 3(1,8) 13(8,20)
Low 0(NaN,NaN) 2(0,7) 9(5,15)
Medium 0(NaN,NaN) 3(1,8) 10(6,16)
High 0(NaN,NaN) 0(NaN,NaN) 15(9,22)
Most deprived 1(0,5) 3(1,8) 31(23,41)

Stratified by age and country

Country Ages 40-49 Ages 50-59 Ages 60-69
England 0(0,2) 1(0,3) 12(10,15)
Scotland 0(NaN,NaN) 4(1,11) 24(15,36)
Wales 0(NaN,NaN) 8(2,21) 35(22,53)

Definition

UK Biobank field id Description Code Value
20002 Non-cancer illness code, self-reported 1120 asbestosis
41202 Diagnoses - main ICD10 J61 Pneumoconiosis due to asbestos and other mineral fibres
41204 Diagnoses - secondary ICD10 J61 Pneumoconiosis due to asbestos and other mineral fibres
40001 Underlying (primary) cause of death: ICD10 J61 Pneumoconiosis due to asbestos and other mineral fibres
40002 Contributory (secondary) causes of death: ICD10 J61 Pneumoconiosis due to asbestos and other mineral fibres
42040 GP clinical event records H410.00 Pleural plaque disease due to asbestosis
42040 GP clinical event records H410.11 Asbestos-induced pleural plaque
42040 GP clinical event records H41..00 Asbestosis
42040 GP clinical event records H41z.00 Asbestosis NOS