| Name |
Bell’s palsy (bells) |
| Category |
Neurological |
| Sex |
|
| Adult |
Yes |
| UUID |
ce8d69cf-b5ce-4ba5-88d1-8cad143f1913 |
| Definition |
Partial or complete paralysis of the facial muscles of one side of a person’s face. It is caused by damage to the seventh cranial nerve. It is usually temporary but it may recur. |
Ontologies
Key Summary Statistics
Cases from any source
| Total |
3173 |
| Female (%) |
1679 (53%) |
| Male (%) |
1494 (47%) |
Year first recorded
Cases linked in all UK Biobank sources
Cross-source concordance
Vertical bars correspond to number of cases per source/intersection; horizontal bars to left correspond to total number of cases per source.
Incidence & prevalence
Baseline prevalence stratified by sex
| Female |
58.11 (53.0,63.23) |
| Male |
56.84 (51.32,62.35) |
Incidence stratified by sex
| Female |
2.72 (2.29,3.15) |
| Male |
3.81 (3.25,4.37) |
Incidence stratified by age
| Ages 40-44 |
3.14 (2.03,4.24) |
| Ages 45-49 |
3.5 (2.5,4.5) |
| Ages 50-54 |
2.8 (1.97,3.63) |
| Ages 55-59 |
3.03 (2.25,3.81) |
| Ages 60-64 |
3.17 (2.48,3.86) |
| Ages 65-69 |
3.64 (2.8,4.48) |
Period prevalence
Methods
Comparison with general population
Sex-standardised prevalence from CALIBER study (Kuan et al. 2019)
| Population |
Ages 40-49 |
Ages 50-59 |
Ages 60-69 |
| UK Biobank |
64 (57,72) |
70 (64,77) |
79 (74,85) |
| CALIBER |
79 (77,81) |
100 (97,103) |
118 (114,121) |
Stratified by age and Townsend deprivation status
| Deprivation status |
Ages 40-49 |
Ages 50-59 |
Ages 60-69 |
| Least deprived |
67(49,90) |
56(44,71) |
68(57,81) |
| Low |
69(51,91) |
67(54,83) |
79(67,93) |
| Medium |
53(38,72) |
70(57,86) |
64(53,76) |
| High |
62(47,81) |
66(53,82) |
84(71,99) |
| Most deprived |
69(54,87) |
90(75,108) |
106(90,123) |
Stratified by age and country
| Country |
Ages 40-49 |
Ages 50-59 |
Ages 60-69 |
| England |
62(54,71) |
68(61,75) |
77(71,84) |
| Scotland |
81(57,111) |
74(57,94) |
99(81,120) |
| Wales |
63(38,99) |
88(64,118) |
71(53,94) |
Risk factors analysis
‘Healthy’ BMI, smoking status ‘never’, or no hypertension (absence of hypertension records) were considered as reference values.
Hazard Ratio (HR) values with P < 0.0002 were considered to show significant association with disease onset after correction for multiple-testing using the Bonferroni method
N=153420, Events=132
| Factor |
Level |
Hazard Ratio |
P value |
| BMI |
overweight |
0.98 (0.66, 1.47) |
0.928 |
| BMI |
obese |
1.08 (0.69, 1.7) |
0.735 |
| BMI |
underweight |
0 (0, Inf) |
0.992 |
| smoking |
previous |
1.16 (0.78, 1.73) |
0.462 |
| smoking |
current |
2.27 (1.45, 3.57) |
0.000355 |
| hypertension |
yes |
1.19 (0.76, 1.85) |
0.449 |
Definition
| UK Biobank field id |
Description |
Code |
Value |
| 20002 |
Non-cancer illness code, self-reported |
1250 |
bell’s palsy/facial nerve palsy |
| 41202 |
Diagnoses - main ICD10 |
G51.0 |
Bell’s palsy |
| 41204 |
Diagnoses - secondary ICD10 |
G51.0 |
Bell’s palsy |
| 40001 |
Underlying (primary) cause of death: ICD10 |
G51.0 |
Bell’s palsy |
| 40002 |
Contributory (secondary) causes of death: ICD10 |
G51.0 |
Bell’s palsy |
| 42040 |
GP clinical event records |
1476 |
H/O: Bell’s palsy |
| 42040 |
GP clinical event records |
F310.00 |
Bell’s (facial) palsy |