Metadata

Name Bifascicular block (bifasc_block)
Category Cardiovascular
Sex
Adult Yes
UUID bf467e6a-9655-4ba6-9562-6a5b1b4eb80d
Definition A conduction abnormality in the heart where two of the three main fascicles of the His/Purkinje system are blocked.

Ontologies

SNOMED-CT 74021003

Key Summary Statistics

Cases from any source

Total 388
Female (%) 84 (22%)
Male (%) 304 (78%)

Year first recorded

bifasc_block year of first event

Cases linked in all UK Biobank sources

Cross-source concordance

Vertical bars correspond to number of cases per source/intersection; horizontal bars to left correspond to total number of cases per source.

Cross-sourced bifasc_block cases

Incidence & prevalence

Baseline prevalence stratified by sex

Female 0.0 (0.0,0.0)
Male 0.28 (-0.11,0.67)

Incidence stratified by sex

Female 0.14 (0.04,0.24)
Male 0.55 (0.34,0.76)

Incidence stratified by age

Ages 40-44 0.0 (0.0,0.0)
Ages 45-49 0.07 (-0.07,0.22)
Ages 50-54 0.06 (-0.06,0.19)
Ages 55-59 0.26 (0.03,0.49)
Ages 60-64 0.35 (0.12,0.57)
Ages 65-69 0.9 (0.49,1.32)

Period prevalence

Methods

Comparison with general population

Sex-standardised prevalence from CALIBER study (Kuan et al. 2019)

CALIBER and UKB bifasc_block prevalence comparison for multiple age groups

Population Ages 40-49 Ages 50-59 Ages 60-69
UK Biobank 0 (0,2) 1 (0,2) 3 (2,5)
CALIBER 3 (3,4)

Stratified by age and Townsend deprivation status

Deprivation status Ages 40-49 Ages 50-59 Ages 60-69
Least deprived 0(NaN,NaN) 1(0,5) 3(1,7)
Low 0(NaN,NaN) 0(NaN,NaN) 4(2,8)
Medium 1(0,6) 2(0,6) 3(1,7)
High 1(0,7) 2(0,5) 2(0,5)
Most deprived 0(NaN,NaN) 2(0,6) 3(1,8)

Stratified by age and country

Country Ages 40-49 Ages 50-59 Ages 60-69
England 1(0,2) 1(0,2) 3(2,5)
Scotland 0(NaN,NaN) 1(0,7) 2(0,8)
Wales 0(NaN,NaN) 2(0,12) 3(0,10)

Definition

UK Biobank field id Description Code Value
41202 Diagnoses - main ICD10 I45.2 Bifascicular block
41204 Diagnoses - secondary ICD10 I45.2 Bifascicular block
40001 Underlying (primary) cause of death: ICD10 I45.2 Bifascicular block
40002 Contributory (secondary) causes of death: ICD10 I45.2 Bifascicular block
42040 GP clinical event records 329F.00 ECG: right bundle branch and left anterior fascicular block
42040 GP clinical event records 329G.00 ECG: right bundle branch and left posterior fascicular block
42040 GP clinical event records G565100 Right BBB with left posterior fascicular block
42040 GP clinical event records G565200 Right BBB with left anterior fascicular block
42040 GP clinical event records XaRCM ECG: right bundle branch and left anterior fascicular block
42040 GP clinical event records XaRCN ECG: right bundle branch and left posterior fascicular block