Infections of the Heart

Metadata

Name	Infections of the Heart (heart)
Category	Infections
Sex
Adult	Yes
UUID	e0d8e0f3-d9ea-4be6-87cc-c9a86a606def
Definition	Infections of the Heart

Ontologies

SNOMED-CT

128403000

Key Summary Statistics

Cases from any source

Total	648
Female (%)	180 (28%)
Male (%)	468 (72%)

Year first recorded

Cases linked in all UK Biobank sources

Cross-source concordance

Vertical bars correspond to number of cases per source/intersection; horizontal bars to left correspond to total number of cases per source.

Incidence & prevalence

Baseline prevalence stratified by sex

Female	1.53 (0.7,2.37)
Male	5.46 (3.75,7.17)

Incidence stratified by sex

Female	0.21 (0.09,0.33)
Male	0.93 (0.65,1.2)

Incidence stratified by age

Ages 40-44	0.2 (-0.08,0.48)
Ages 45-49	0.07 (-0.07,0.22)
Ages 50-54	0.25 (0.01,0.5)
Ages 55-59	0.36 (0.09,0.63)
Ages 60-64	1.0 (0.61,1.38)
Ages 65-69	0.8 (0.41,1.2)

Period prevalence

Methods

Comparison with general population

Sex-standardised prevalence from CALIBER study (Kuan et al. 2019)

Population	Ages 40-49	Ages 50-59	Ages 60-69
UK Biobank	3 (2,5)	5 (3,7)	9 (7,11)
CALIBER	5 (5,6)	6 (5,7)	9 (8,10)

Stratified by age and Townsend deprivation status

Deprivation status	Ages 40-49	Ages 50-59	Ages 60-69
Least deprived	3(0,9)	5(2,11)	8(4,13)
Low	6(2,15)	4(1,9)	13(8,19)
Medium	3(0,11)	6(3,13)	6(3,11)
High	2(0,8)	2(0,6)	8(4,13)
Most deprived	3(1,9)	8(4,14)	12(7,19)

Stratified by age and country

Country	Ages 40-49	Ages 50-59	Ages 60-69
England	3(1,6)	6(4,8)	9(7,12)
Scotland	2(0,10)	1(0,6)	9(4,17)
Wales	7(1,24)	4(0,14)	7(2,17)

Definition

UK Biobank field id	Description	Code	Value
41202	Diagnoses - main ICD10	A39.5	Meningococcal heart disease
41202	Diagnoses - main ICD10	A52.0	Cardiovascular syphilis
41202	Diagnoses - main ICD10	B33.2	Viral carditis
41202	Diagnoses - main ICD10	B37.6	Candidal endocarditis
41202	Diagnoses - main ICD10	I30.1	Infective pericarditis
41202	Diagnoses - main ICD10	I32.0	Pericarditis in bacterial diseases classified elsewhere
41202	Diagnoses - main ICD10	I32.1	Pericarditis in other infectious and parasitic diseases classified elsewhere
41202	Diagnoses - main ICD10	I33.0	Acute and subacute infective endocarditis
41202	Diagnoses - main ICD10	I40.0	Infective myocarditis
41202	Diagnoses - main ICD10	I41.0	Myocarditis in bacterial diseases classified elsewhere
41202	Diagnoses - main ICD10	I41.1	Myocarditis in viral diseases classified elsewhere
41202	Diagnoses - main ICD10	I41.2	Myocarditis in other infectious and parasitic diseases classified elsewhere
41202	Diagnoses - main ICD10	I43.0	Cardiomyopathy in infectious and parasitic diseases classified elsewhere
41202	Diagnoses - main ICD10	I98.0	Cardiovascular syphilis
41202	Diagnoses - main ICD10	I98.1	Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
41204	Diagnoses - secondary ICD10	A39.5	Meningococcal heart disease
41204	Diagnoses - secondary ICD10	A52.0	Cardiovascular syphilis
41204	Diagnoses - secondary ICD10	B33.2	Viral carditis
41204	Diagnoses - secondary ICD10	B37.6	Candidal endocarditis
41204	Diagnoses - secondary ICD10	I30.1	Infective pericarditis
41204	Diagnoses - secondary ICD10	I32.0	Pericarditis in bacterial diseases classified elsewhere
41204	Diagnoses - secondary ICD10	I32.1	Pericarditis in other infectious and parasitic diseases classified elsewhere
41204	Diagnoses - secondary ICD10	I33.0	Acute and subacute infective endocarditis
41204	Diagnoses - secondary ICD10	I40.0	Infective myocarditis
41204	Diagnoses - secondary ICD10	I41.0	Myocarditis in bacterial diseases classified elsewhere
41204	Diagnoses - secondary ICD10	I41.1	Myocarditis in viral diseases classified elsewhere
41204	Diagnoses - secondary ICD10	I41.2	Myocarditis in other infectious and parasitic diseases classified elsewhere
41204	Diagnoses - secondary ICD10	I43.0	Cardiomyopathy in infectious and parasitic diseases classified elsewhere
41204	Diagnoses - secondary ICD10	I98.0	Cardiovascular syphilis
41204	Diagnoses - secondary ICD10	I98.1	Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
40001	Underlying (primary) cause of death: ICD10	A39.5	Meningococcal heart disease
40001	Underlying (primary) cause of death: ICD10	A52.0	Cardiovascular syphilis
40001	Underlying (primary) cause of death: ICD10	B33.2	Viral carditis
40001	Underlying (primary) cause of death: ICD10	B37.6	Candidal endocarditis
40001	Underlying (primary) cause of death: ICD10	I30.1	Infective pericarditis
40001	Underlying (primary) cause of death: ICD10	I32.0	Pericarditis in bacterial diseases classified elsewhere
40001	Underlying (primary) cause of death: ICD10	I32.1	Pericarditis in other infectious and parasitic diseases classified elsewhere
40001	Underlying (primary) cause of death: ICD10	I33.0	Acute and subacute infective endocarditis
40001	Underlying (primary) cause of death: ICD10	I40.0	Infective myocarditis
40001	Underlying (primary) cause of death: ICD10	I41.0	Myocarditis in bacterial diseases classified elsewhere
40001	Underlying (primary) cause of death: ICD10	I41.1	Myocarditis in viral diseases classified elsewhere
40001	Underlying (primary) cause of death: ICD10	I41.2	Myocarditis in other infectious and parasitic diseases classified elsewhere
40001	Underlying (primary) cause of death: ICD10	I43.0	Cardiomyopathy in infectious and parasitic diseases classified elsewhere
40001	Underlying (primary) cause of death: ICD10	I98.0	Cardiovascular syphilis
40001	Underlying (primary) cause of death: ICD10	I98.1	Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
40002	Contributory (secondary) causes of death: ICD10	A39.5	Meningococcal heart disease
40002	Contributory (secondary) causes of death: ICD10	A52.0	Cardiovascular syphilis
40002	Contributory (secondary) causes of death: ICD10	B33.2	Viral carditis
40002	Contributory (secondary) causes of death: ICD10	B37.6	Candidal endocarditis
40002	Contributory (secondary) causes of death: ICD10	I30.1	Infective pericarditis
40002	Contributory (secondary) causes of death: ICD10	I32.0	Pericarditis in bacterial diseases classified elsewhere
40002	Contributory (secondary) causes of death: ICD10	I32.1	Pericarditis in other infectious and parasitic diseases classified elsewhere
40002	Contributory (secondary) causes of death: ICD10	I33.0	Acute and subacute infective endocarditis
40002	Contributory (secondary) causes of death: ICD10	I40.0	Infective myocarditis
40002	Contributory (secondary) causes of death: ICD10	I41.0	Myocarditis in bacterial diseases classified elsewhere
40002	Contributory (secondary) causes of death: ICD10	I41.1	Myocarditis in viral diseases classified elsewhere
40002	Contributory (secondary) causes of death: ICD10	I41.2	Myocarditis in other infectious and parasitic diseases classified elsewhere
40002	Contributory (secondary) causes of death: ICD10	I43.0	Cardiomyopathy in infectious and parasitic diseases classified elsewhere
40002	Contributory (secondary) causes of death: ICD10	I98.0	Cardiovascular syphilis
40002	Contributory (secondary) causes of death: ICD10	I98.1	Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere