| Name |
Hypertrophy of nasal turbinates (hyper_nasal_turbs) |
| Category |
Respiratory |
| Sex |
|
| Adult |
Yes |
| UUID |
1acb3537-fd98-4cf4-92cb-fe85f6e15294 |
| Definition |
A condition where the tissue on the lateral (outside) walls of the nose are too large, causing nasal obstruction. |
Ontologies
Key Summary Statistics
Cases from any source
| Total |
2600 |
| Female (%) |
1084 (42%) |
| Male (%) |
1516 (58%) |
Year first recorded
Cases linked in all UK Biobank sources
Cross-source concordance
Vertical bars correspond to number of cases per source/intersection; horizontal bars to left correspond to total number of cases per source.
Incidence & prevalence
Baseline prevalence stratified by sex
| Female |
23.34 (20.09,26.59) |
| Male |
46.34 (41.36,51.32) |
Incidence stratified by sex
| Female |
1.06 (0.79,1.32) |
| Male |
2.07 (1.66,2.48) |
Incidence stratified by age
| Ages 40-44 |
1.82 (0.98,2.66) |
| Ages 45-49 |
1.64 (0.95,2.32) |
| Ages 50-54 |
2.41 (1.65,3.18) |
| Ages 55-59 |
1.41 (0.88,1.94) |
| Ages 60-64 |
1.12 (0.71,1.52) |
| Ages 65-69 |
1.21 (0.72,1.69) |
Period prevalence
Methods
Comparison with general population
Sex-standardised prevalence from CALIBER study (Kuan et al. 2019)
| Population |
Ages 40-49 |
Ages 50-59 |
Ages 60-69 |
| UK Biobank |
57 (50,65) |
50 (45,56) |
40 (36,44) |
| CALIBER |
49 (47,51) |
44 (42,46) |
35 (34,37) |
Stratified by age and Townsend deprivation status
| Deprivation status |
Ages 40-49 |
Ages 50-59 |
Ages 60-69 |
| Least deprived |
46(32,65) |
39(29,51) |
34(27,44) |
| Low |
51(35,70) |
49(38,64) |
44(35,55) |
| Medium |
59(43,80) |
47(36,61) |
41(32,52) |
| High |
59(44,78) |
54(42,69) |
35(26,45) |
| Most deprived |
64(49,81) |
62(50,77) |
44(34,56) |
Stratified by age and country
| Country |
Ages 40-49 |
Ages 50-59 |
Ages 60-69 |
| England |
63(55,72) |
53(47,60) |
45(40,50) |
| Scotland |
21(10,38) |
38(26,53) |
18(10,28) |
| Wales |
48(26,80) |
45(29,68) |
20(11,34) |
Risk factors analysis
‘Healthy’ BMI, smoking status ‘never’, or no hypertension (absence of hypertension records) were considered as reference values.
Hazard Ratio (HR) values with P < 0.0002 were considered to show significant association with disease onset after correction for multiple-testing using the Bonferroni method
N=153513, Events=116
| Factor |
Level |
Hazard Ratio |
P value |
| BMI |
overweight |
1.85 (1.14, 2.99) |
0.0128 |
| BMI |
obese |
1.9 (1.12, 3.22) |
0.0174 |
| BMI |
underweight |
0 (0, Inf) |
0.993 |
| smoking |
previous |
0.82 (0.53, 1.27) |
0.367 |
| smoking |
current |
1.79 (1.09, 2.95) |
0.0215 |
| hypertension |
yes |
1.55 (1.01, 2.37) |
0.0432 |
Definition
| UK Biobank field id |
Description |
Code |
Value |
| 41202 |
Diagnoses - main ICD10 |
J34.3 |
Hypertrophy of nasal turbinates |
| 41204 |
Diagnoses - secondary ICD10 |
J34.3 |
Hypertrophy of nasal turbinates |
| 40001 |
Underlying (primary) cause of death: ICD10 |
J34.3 |
Hypertrophy of nasal turbinates |
| 40002 |
Contributory (secondary) causes of death: ICD10 |
J34.3 |
Hypertrophy of nasal turbinates |
| 42040 |
GP clinical event records |
H1y0.00 |
Nasal turbinate hypertrophy |