| Name |
Infection of male genital system (male_GU) |
| Category |
Infections |
| Sex |
|
| Adult |
Yes |
| UUID |
a89dc179-24ec-444f-8631-583fd10d28b2 |
| Definition |
Infection of male genital system |
Ontologies
Key Summary Statistics
Cases from any source
| Total |
2520 |
| Female (%) |
0 (0%) |
| Male (%) |
2520 (100%) |
Year first recorded
Cases linked in all UK Biobank sources
*All 802 cases from Hospital EHR*
Incidence & prevalence
Baseline prevalence stratified by sex
| Female |
0.0 (0.0,0.0) |
| Male |
40.04 (35.41,44.67) |
Incidence stratified by sex
| Female |
0.0 (0.0,0.0) |
| Male |
4.89 (4.26,5.52) |
Incidence stratified by age
| Ages 40-44 |
1.71 (0.9,2.53) |
| Ages 45-49 |
1.63 (0.95,2.32) |
| Ages 50-54 |
1.52 (0.91,2.13) |
| Ages 55-59 |
2.03 (1.39,2.67) |
| Ages 60-64 |
2.58 (1.96,3.19) |
| Ages 65-69 |
3.12 (2.34,3.9) |
Period prevalence
Methods
Comparison with general population
Sex-standardised prevalence from CALIBER study (Kuan et al. 2019)
| Population |
Ages 40-49 |
Ages 50-59 |
Ages 60-69 |
| UK Biobank |
32 (27,39) |
30 (26,35) |
40 (36,44) |
| CALIBER |
59 (57,62) |
57 (54,60) |
69 (66,73) |
Stratified by age and Townsend deprivation status
| Deprivation status |
Ages 40-49 |
Ages 50-59 |
Ages 60-69 |
| Least deprived |
28(16,44) |
24(16,35) |
32(24,41) |
| Low |
30(18,47) |
31(21,43) |
42(33,52) |
| Medium |
27(16,42) |
27(18,38) |
34(25,43) |
| High |
31(20,46) |
25(17,36) |
43(33,55) |
| Most deprived |
42(30,57) |
43(32,56) |
51(40,64) |
Stratified by age and country
| Country |
Ages 40-49 |
Ages 50-59 |
Ages 60-69 |
| England |
32(26,39) |
30(25,35) |
38(34,43) |
| Scotland |
44(26,68) |
40(27,56) |
43(31,58) |
| Wales |
22(8,48) |
17(7,34) |
49(34,69) |
Risk factors analysis
‘Healthy’ BMI, smoking status ‘never’, or no hypertension (absence of hypertension records) were considered as reference values.
Hazard Ratio (HR) values with P < 0.0002 were considered to show significant association with disease onset after correction for multiple-testing using the Bonferroni method
N=153969, Events=129
| Factor |
Level |
Hazard Ratio |
P value |
| BMI |
overweight |
1.18 (0.74, 1.86) |
0.489 |
| BMI |
obese |
1.91 (1.2, 3.06) |
0.00685 |
| BMI |
underweight |
0 (0, Inf) |
0.995 |
| smoking |
previous |
1.29 (0.88, 1.87) |
0.189 |
| smoking |
current |
1.41 (0.81, 2.45) |
0.23 |
| hypertension |
yes |
1.93 (1.34, 2.77) |
0.000403 |
Definition
| UK Biobank field id |
Description |
Code |
Value |
| 41202 |
Diagnoses - main ICD10 |
B26.0 |
Mumps orchitis |
| 41202 |
Diagnoses - main ICD10 |
N41.0 |
Acute prostatitis |
| 41202 |
Diagnoses - main ICD10 |
N41.2 |
Abscess of prostate |
| 41202 |
Diagnoses - main ICD10 |
N41.3 |
Prostatocystitis |
| 41202 |
Diagnoses - main ICD10 |
N43.1 |
Infected hydrocele |
| 41202 |
Diagnoses - main ICD10 |
N45 |
Orchitis and epididymitis |
| 41202 |
Diagnoses - main ICD10 |
N48.1 |
Balanoposthitis |
| 41204 |
Diagnoses - secondary ICD10 |
B26.0 |
Mumps orchitis |
| 41204 |
Diagnoses - secondary ICD10 |
N41.0 |
Acute prostatitis |
| 41204 |
Diagnoses - secondary ICD10 |
N41.2 |
Abscess of prostate |
| 41204 |
Diagnoses - secondary ICD10 |
N41.3 |
Prostatocystitis |
| 41204 |
Diagnoses - secondary ICD10 |
N43.1 |
Infected hydrocele |
| 41204 |
Diagnoses - secondary ICD10 |
N45 |
Orchitis and epididymitis |
| 41204 |
Diagnoses - secondary ICD10 |
N48.1 |
Balanoposthitis |
| 40001 |
Underlying (primary) cause of death: ICD10 |
B26.0 |
Mumps orchitis |
| 40001 |
Underlying (primary) cause of death: ICD10 |
N41.0 |
Acute prostatitis |
| 40001 |
Underlying (primary) cause of death: ICD10 |
N41.2 |
Abscess of prostate |
| 40001 |
Underlying (primary) cause of death: ICD10 |
N41.3 |
Prostatocystitis |
| 40001 |
Underlying (primary) cause of death: ICD10 |
N43.1 |
Infected hydrocele |
| 40001 |
Underlying (primary) cause of death: ICD10 |
N45 |
Orchitis and epididymitis |
| 40001 |
Underlying (primary) cause of death: ICD10 |
N48.1 |
Balanoposthitis |
| 40002 |
Contributory (secondary) causes of death: ICD10 |
B26.0 |
Mumps orchitis |
| 40002 |
Contributory (secondary) causes of death: ICD10 |
N41.0 |
Acute prostatitis |
| 40002 |
Contributory (secondary) causes of death: ICD10 |
N41.2 |
Abscess of prostate |
| 40002 |
Contributory (secondary) causes of death: ICD10 |
N41.3 |
Prostatocystitis |
| 40002 |
Contributory (secondary) causes of death: ICD10 |
N43.1 |
Infected hydrocele |
| 40002 |
Contributory (secondary) causes of death: ICD10 |
N45 |
Orchitis and epididymitis |
| 40002 |
Contributory (secondary) causes of death: ICD10 |
N48.1 |
Balanoposthitis |