Metadata
| Name | Obsessive-compulsive disorder (ocd) |
| Category | Psychiatric |
| Sex | |
| Adult | Yes |
| UUID | 0206f3ef-9b74-4bbc-8fda-fe4aa1651213 |
| Definition | Obsessive-compulsive disorder (OCD) is a mental illness that causes repeated unwanted thoughts or sensations (obsessions) or the urge to do something over and over again (compulsions). |
Ontologies
| Disease Ontology (DOID) | DOID_10933 |
| GWAS Catalogue | EFO_0004242 |
| MeSH | D009771 |
| SNOMED-CT | 191736004 |
| FinnGen | F5_OCD |
Key Summary Statistics
Cases from any source
| Total | 1769 |
| Female (%) | 1036 (59%) |
| Male (%) | 733 (41%) |
Year first recorded
Cases linked in all UK Biobank sources
Cross-source concordance
Vertical bars correspond to number of cases per source/intersection; horizontal bars to left correspond to total number of cases per source.
Incidence & prevalence
Baseline prevalence stratified by sex
| Female | 43.5 (39.07,47.93) |
| Male | 35.14 (30.8,39.48) |
Incidence stratified by sex
| Female | 0.51 (0.33,0.7) |
| Male | 0.44 (0.25,0.63) |
Incidence stratified by age
| Ages 40-44 | 0.81 (0.25,1.37) |
| Ages 45-49 | 0.3 (0.01,0.59) |
| Ages 50-54 | 1.02 (0.52,1.52) |
| Ages 55-59 | 0.37 (0.09,0.64) |
| Ages 60-64 | 0.38 (0.15,0.62) |
| Ages 65-69 | 0.25 (0.03,0.47) |
Period prevalence
Methods
Comparison with general population
Sex-standardised prevalence from CALIBER study (Kuan et al. 2019)
| Population | Ages 40-49 | Ages 50-59 | Ages 60-69 |
| UK Biobank | 35 (30,42) | 30 (26,35) | 21 (18,24) |
| CALIBER | 58 (56,60) | 47 (45,49) | 35 (33,37) |
Stratified by age and Townsend deprivation status
| Deprivation status | Ages 40-49 | Ages 50-59 | Ages 60-69 |
| Least deprived | 24(14,38) | 28(20,39) | 21(15,28) |
| Low | 34(22,51) | 26(18,36) | 19(13,26) |
| Medium | 21(12,34) | 25(17,35) | 21(15,29) |
| High | 36(25,51) | 30(21,41) | 20(14,28) |
| Most deprived | 52(39,68) | 41(31,53) | 23(16,32) |
Stratified by age and country
| Country | Ages 40-49 | Ages 50-59 | Ages 60-69 |
| England | 36(30,43) | 32(28,37) | 20(17,23) |
| Scotland | 35(20,55) | 14(8,24) | 20(12,30) |
| Wales | 34(16,62) | 37(22,57) | 31(19,47) |
Definition
| UK Biobank field id | Description | Code | Value |
|---|---|---|---|
| 20002 | Non-cancer illness code, self-reported | 1615 | obsessive compulsive disorder (ocd) |
| 41202 | Diagnoses - main ICD10 | F42 | Obsessive-compulsive disorder |
| 41204 | Diagnoses - secondary ICD10 | F42 | Obsessive-compulsive disorder |
| 40001 | Underlying (primary) cause of death: ICD10 | F42 | Obsessive-compulsive disorder |
| 40002 | Contributory (secondary) causes of death: ICD10 | F42 | Obsessive-compulsive disorder |
| 42040 | GP clinical event records | E203000 | Compulsive neurosis |
| 42040 | GP clinical event records | E203100 | Obsessional neurosis |
| 42040 | GP clinical event records | E203.00 | Obsessive-compulsive disorders |
| 42040 | GP clinical event records | E203.11 | Anancastic neurosis |
| 42040 | GP clinical event records | E203z00 | Obsessive-compulsive disorder NOS |
| 42040 | GP clinical event records | Eu42000 | [X]Predominantly obsessional thoughts or ruminations |
| 42040 | GP clinical event records | Eu42100 | [X]Predominantly compulsive acts [obsessional rituals] |
| 42040 | GP clinical event records | Eu42200 | [X]Mixed obsessional thoughts and acts |
| 42040 | GP clinical event records | Eu42.00 | [X]Obsessive - compulsive disorder |
| 42040 | GP clinical event records | Eu42.11 | [X]Anankastic neurosis |
| 42040 | GP clinical event records | Eu42.12 | [X]Obsessive-compulsive neurosis |
| 42040 | GP clinical event records | Eu42y00 | [X]Other obsessive-compulsive disorders |
| 42040 | GP clinical event records | Eu42z00 | [X]Obsessive-compulsive disorder, unspecified |
| 20544 | Mental health problems ever diagnosed by a professional | 7 | OCD |