| Name |
Polycystic ovarian syndrome (PCOS) |
| Category |
Endocrine |
| Sex |
|
| Adult |
Yes |
| UUID |
99013c8a-fae6-4f8a-8448-f477d7c0cabe |
| Definition |
A complex disorder characterized by infertility, HIRSUTISM; OBESITY; and various menstrual disturbances such as OLIGOMENORRHEA; AMENORRHEA; ANOVULATION. |
Ontologies
Key Summary Statistics
Cases from any source
| Total |
1287 |
| Female (%) |
1287 (100%) |
| Male (%) |
0 (0%) |
Year first recorded
Cases linked in all UK Biobank sources
Cross-source concordance
Vertical bars correspond to number of cases per source/intersection; horizontal bars to left correspond to total number of cases per source.
Incidence & prevalence
Baseline prevalence stratified by sex
| Female |
55.99 (50.97,61.01) |
| Male |
0.0 (0.0,0.0) |
Incidence stratified by sex
| Female |
0.28 (0.14,0.42) |
| Male |
0.0 (0.0,0.0) |
Incidence stratified by age
| Ages 40-44 |
0.3 (-0.04,0.65) |
| Ages 45-49 |
0.15 (-0.06,0.36) |
| Ages 50-54 |
0.32 (0.04,0.6) |
| Ages 55-59 |
0.16 (-0.02,0.33) |
| Ages 60-64 |
0.0 (0.0,0.0) |
| Ages 65-69 |
0.15 (-0.02,0.32) |
Period prevalence
Methods
Comparison with general population
Sex-standardised prevalence from CALIBER study (Kuan et al. 2019)
| Population |
Ages 40-49 |
Ages 50-59 |
Ages 60-69 |
| UK Biobank |
69 (61,77) |
20 (17,23) |
5 (4,6) |
| CALIBER |
86 (83,90) |
20 (18,22) |
7 (6,8) |
Stratified by age and Townsend deprivation status
| Deprivation status |
Ages 40-49 |
Ages 50-59 |
Ages 60-69 |
| Least deprived |
67(50,87) |
19(12,27) |
3(1,6) |
| Low |
54(39,73) |
21(14,29) |
3(1,7) |
| Medium |
69(52,89) |
13(8,20) |
6(3,10) |
| High |
64(49,82) |
24(17,33) |
5(2,9) |
| Most deprived |
85(68,104) |
23(16,32) |
8(4,13) |
Stratified by age and country
| Country |
Ages 40-49 |
Ages 50-59 |
Ages 60-69 |
| England |
69(61,78) |
21(18,25) |
5(3,6) |
| Scotland |
67(48,92) |
22(14,33) |
9(5,16) |
| Wales |
63(39,97) |
5(1,15) |
0(NaN,NaN) |
Definition
| UK Biobank field id |
Description |
Code |
Value |
| 20002 |
Non-cancer illness code, self-reported |
1350 |
polycystic ovaries/polycystic ovarian syndrome |
| 41202 |
Diagnoses - main ICD10 |
E28.2 |
Polycystic ovarian syndrome |
| 41204 |
Diagnoses - secondary ICD10 |
E28.2 |
Polycystic ovarian syndrome |
| 40001 |
Underlying (primary) cause of death: ICD10 |
E28.2 |
Polycystic ovarian syndrome |
| 40002 |
Contributory (secondary) causes of death: ICD10 |
E28.2 |
Polycystic ovarian syndrome |
| 42040 |
GP clinical event records |
C164.12 |
Stein - Leventhal syndrome |
| 42040 |
GP clinical event records |
C165.00 |
Polycystic ovarian syndrome |
| 42040 |
GP clinical event records |
XE10l |
Polycystic ovaries |