Posterior Uveitis

Metadata

Name	Posterior Uveitis (post_uveitis)
Category	Eye
Sex
Adult	Yes
UUID	9fb1754f-0d72-494a-9fdd-f0336239956e
Definition	Inflammation of the choroid as well as the retina and vitreous body.

Ontologies

Disease Ontology (DOID)	DOID_12574
MeSH	D015866
SNOMED-CT	43363007

Key Summary Statistics

Cases from any source

Total	280
Female (%)	153 (55%)
Male (%)	127 (45%)

Year first recorded

Cases linked in all UK Biobank sources

Cross-source concordance

Vertical bars correspond to number of cases per source/intersection; horizontal bars to left correspond to total number of cases per source.

Incidence & prevalence

Baseline prevalence stratified by sex

Female	6.6 (4.87,8.33)
Male	7.84 (5.79,9.89)

Incidence stratified by sex

Female	0.4 (0.24,0.57)
Male	0.23 (0.09,0.37)

Incidence stratified by age

Ages 40-44	0.4 (0.01,0.8)
Ages 45-49	0.22 (-0.03,0.47)
Ages 50-54	0.38 (0.08,0.68)
Ages 55-59	0.21 (0.0,0.41)
Ages 60-64	0.27 (0.07,0.47)
Ages 65-69	0.5 (0.19,0.81)

Period prevalence

Methods

Comparison with general population

Sex-standardised prevalence from CALIBER study (Kuan et al. 2019)

Population	Ages 40-49	Ages 50-59	Ages 60-69
UK Biobank	8 (5,11)	10 (8,13)	11 (9,13)
CALIBER	6 (6,7)	8 (7,9)	9 (8,10)

Stratified by age and Townsend deprivation status

Deprivation status	Ages 40-49	Ages 50-59	Ages 60-69
Least deprived	6(2,14)	6(3,12)	9(5,14)
Low	4(1,11)	10(5,17)	11(7,17)
Medium	3(0,10)	13(8,21)	10(6,16)
High	9(4,17)	9(5,16)	11(6,17)
Most deprived	16(9,25)	12(7,20)	15(10,23)

Stratified by age and country

Country	Ages 40-49	Ages 50-59	Ages 60-69
England	7(5,11)	9(6,12)	10(8,13)
Scotland	12(4,25)	15(8,25)	13(7,21)
Wales	10(2,31)	16(7,30)	14(7,27)

Definition

UK Biobank field id	Description	Code	Value
41202	Diagnoses - main ICD10	H30.0	Focal chorioretinal inflammation
41202	Diagnoses - main ICD10	H30.1	Disseminated chorioretinal inflammation
41202	Diagnoses - main ICD10	H30.8	Other chorioretinal inflammations
41202	Diagnoses - main ICD10	H30.9	Chorioretinal inflammation, unspecified
41202	Diagnoses - main ICD10	H32.0	Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere
41204	Diagnoses - secondary ICD10	H30.0	Focal chorioretinal inflammation
41204	Diagnoses - secondary ICD10	H30.1	Disseminated chorioretinal inflammation
41204	Diagnoses - secondary ICD10	H30.8	Other chorioretinal inflammations
41204	Diagnoses - secondary ICD10	H30.9	Chorioretinal inflammation, unspecified
41204	Diagnoses - secondary ICD10	H32.0	Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere
40001	Underlying (primary) cause of death: ICD10	H30.0	Focal chorioretinal inflammation
40001	Underlying (primary) cause of death: ICD10	H30.1	Disseminated chorioretinal inflammation
40001	Underlying (primary) cause of death: ICD10	H30.8	Other chorioretinal inflammations
40001	Underlying (primary) cause of death: ICD10	H30.9	Chorioretinal inflammation, unspecified
40001	Underlying (primary) cause of death: ICD10	H32.0	Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere
40002	Contributory (secondary) causes of death: ICD10	H30.0	Focal chorioretinal inflammation
40002	Contributory (secondary) causes of death: ICD10	H30.1	Disseminated chorioretinal inflammation
40002	Contributory (secondary) causes of death: ICD10	H30.8	Other chorioretinal inflammations
40002	Contributory (secondary) causes of death: ICD10	H30.9	Chorioretinal inflammation, unspecified
40002	Contributory (secondary) causes of death: ICD10	H32.0	Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere
42040	GP clinical event records	A173000	Tuberculous chorioretinitis
42040	GP clinical event records	A900.12	Congenital syphilitic choroiditis
42040	GP clinical event records	A915100	Secondary syphilitic chorioretinitis
42040	GP clinical event records	A94y200	Syphilitic disseminated retinochoroiditis
42040	GP clinical event records	AD02.00	Toxoplasma chorioretinitis
42040	GP clinical event records	F401000	Sympathetic uveitis
42040	GP clinical event records	F401100	Panuveitis
42040	GP clinical event records	F430000	Unspecified focal chorioretinitis
42040	GP clinical event records	F430100	Focal juxtapapillary choroiditis
42040	GP clinical event records	F430200	Other posterior pole focal chorioretinitis
42040	GP clinical event records	F430300	Peripheral focal chorioretinitis
42040	GP clinical event records	F430400	Focal juxtapapillary retinitis
42040	GP clinical event records	F430500	Focal macular retinochoroiditis
42040	GP clinical event records	F430600	Other posterior pole focal retinitis
42040	GP clinical event records	F430700	Peripheral focal retinochoroiditis
42040	GP clinical event records	F430800	Multifocal choroiditis
42040	GP clinical event records	F430.00	Focal chorioretinitis and retinochoroiditis
42040	GP clinical event records	F430.11	Retinitis and chorioretinitis
42040	GP clinical event records	F430z00	Focal chorioretinitis or retinochoroiditis NOS
42040	GP clinical event records	F431000	Unspecified disseminated chorioretinitis
42040	GP clinical event records	F431300	General disseminated chorioretinitis
42040	GP clinical event records	F431400	Metastatic disseminated retinitis
42040	GP clinical event records	F431500	Pigmented epithelial disseminated retinitis
42040	GP clinical event records	F431600	Punctate inner choroidopathy
42040	GP clinical event records	F431.00	Disseminated chorioretinitis and retinochoroiditis
42040	GP clinical event records	F431z00	Disseminated chorioretinitis and retinochoroiditis NOS
42040	GP clinical event records	F432000	Choroiditis NOS
42040	GP clinical event records	F432100	Retinitis NOS
42040	GP clinical event records	F432200	Posterior uveitis NOS
42040	GP clinical event records	F432400	Harada’s disease
42040	GP clinical event records	F432.00	Other chorioretinitis and retinochoroiditis
42040	GP clinical event records	F432z00	Other chorioretinitis or retinochoroiditis NOS
42040	GP clinical event records	F442300	Vogt-Koyanagi syndrome
42040	GP clinical event records	FyuF000	[X]Other chorioretinal inflammations
42040	GP clinical event records	XE0Ri	Early congenital syphilis with symptoms
42040	GP clinical event records	XaE6M	Punctate inner choroidopathy
42040	GP clinical event records	XaQIm	Multifocal choroiditis