Metadata
| Name | Primary Malignancy of Testicular (pri_testis) |
| Category | Cancers |
| Sex | |
| Adult | Yes |
| UUID | 30cc2a27-febf-4adc-adba-bb2fc1873791 |
| Definition | A primary or metastatic malignant neoplasm that affects the testis. |
Ontologies
| Disease Ontology (DOID) | DOID_2998 |
| GWAS Catalogue | EFO_0005088 |
| MeSH | D013736 |
| SNOMED-CT | 315272007 |
| FinnGen | C3_TESTIS |
Key Summary Statistics
Cases from any source
| Total | 994 |
| Female (%) | 0 (0%) |
| Male (%) | 994 (100%) |
Year first recorded
Cases linked in all UK Biobank sources
Cross-source concordance
Vertical bars correspond to number of cases per source/intersection; horizontal bars to left correspond to total number of cases per source.
Incidence & prevalence
Baseline prevalence stratified by sex
| Female | 0.0 (0.0,0.0) |
| Male | 41.44 (36.73,46.15) |
Incidence stratified by sex
| Female | 0.0 (0.0,0.0) |
| Male | 0.61 (0.39,0.84) |
Incidence stratified by age
| Ages 40-44 | 0.6 (0.12,1.09) |
| Ages 45-49 | 0.59 (0.18,1.01) |
| Ages 50-54 | 0.13 (-0.05,0.3) |
| Ages 55-59 | 0.1 (-0.04,0.25) |
| Ages 60-64 | 0.27 (0.07,0.47) |
| Ages 65-69 | 0.2 (0.0,0.4) |
Period prevalence
Methods
Comparison with general population
Sex-standardised prevalence from CALIBER study (Kuan et al. 2019)
| Population | Ages 40-49 | Ages 50-59 | Ages 60-69 |
| UK Biobank | 25 (21,31) | 18 (15,22) | 11 (9,14) |
| CALIBER | 29 (27,31) | 26 (24,28) | 19 (17,20) |
Stratified by age and Townsend deprivation status
| Deprivation status | Ages 40-49 | Ages 50-59 | Ages 60-69 |
| Least deprived | 26(15,42) | 22(14,32) | 15(10,22) |
| Low | 30(18,47) | 18(11,28) | 9(5,15) |
| Medium | 35(23,53) | 18(11,27) | 8(4,13) |
| High | 25(15,38) | 19(12,29) | 7(4,13) |
| Most deprived | 16(9,26) | 15(9,24) | 16(10,24) |
Stratified by age and country
| Country | Ages 40-49 | Ages 50-59 | Ages 60-69 |
| England | 24(19,31) | 17(14,22) | 11(9,14) |
| Scotland | 32(18,54) | 28(18,43) | 12(6,21) |
| Wales | 26(10,53) | 11(4,25) | 8(2,18) |
Definition
| UK Biobank field id | Description | Code | Value |
|---|---|---|---|
| 20001 | Cancer code, self-reported | 1045 | testicular cancer |
| 41202 | Diagnoses - main ICD10 | C62 | Malignant neoplasm of testis |
| 41204 | Diagnoses - secondary ICD10 | C62 | Malignant neoplasm of testis |
| 40001 | Underlying (primary) cause of death: ICD10 | C62 | Malignant neoplasm of testis |
| 40002 | Contributory (secondary) causes of death: ICD10 | C62 | Malignant neoplasm of testis |
| 42040 | GP clinical event records | B470200 | Seminoma of undescended testis |
| 42040 | GP clinical event records | B470300 | Teratoma of undescended testis |
| 42040 | GP clinical event records | B470.00 | Malignant neoplasm of undescended testis |
| 42040 | GP clinical event records | B470z00 | Malignant neoplasm of undescended testis NOS |
| 42040 | GP clinical event records | B471000 | Seminoma of descended testis |
| 42040 | GP clinical event records | B471100 | Teratoma of descended testis |
| 42040 | GP clinical event records | B471.00 | Malignant neoplasm of descended testis |
| 42040 | GP clinical event records | B471z00 | Malignant neoplasm of descended testis NOS |
| 42040 | GP clinical event records | B47..00 | Malignant neoplasm of testis |
| 42040 | GP clinical event records | B47z.00 | Malignant neoplasm of testis NOS |
| 42040 | GP clinical event records | B47z.11 | Seminoma of testis |
| 42040 | GP clinical event records | B47z.12 | Teratoma of testis |
| 42040 | GP clinical event records | ZV10416 | [V]Personal history of malignant neoplasm of testis |
| 42040 | GP clinical event records | XaELL | Teratoma of descended testis |
| 42040 | GP clinical event records | XaELK | Seminoma of descended testis |
| 42040 | GP clinical event records | XaMeL | Malignant neoplasm of descended testis NOS |
| 42040 | GP clinical event records | XaELM | Teratoma of undescended testis |
| 42040 | GP clinical event records | XaELJ | Seminoma of undescended testis |
| 42040 | GP clinical event records | XE1vk | Malignant neoplasm of testis NOS |
| 40006 | Type of cancer: ICD10 | C62 | Malignant neoplasm of testis |