| Name |
Pulmonary collapse (excl pneumothorax) (pulm_collapse) |
| Category |
Respiratory |
| Sex |
|
| Adult |
Yes |
| UUID |
d6f174a3-396c-4e24-9b8c-ef485f222bbb |
| Definition |
Absence of air in the entire or part of a lung, such as an incompletely inflated neonate lung or a collapsed adult lung. |
Ontologies
Key Summary Statistics
Cases from any source
| Total |
7903 |
| Female (%) |
3715 (47%) |
| Male (%) |
4188 (53%) |
Year first recorded
Cases linked in all UK Biobank sources
Cross-source concordance
Vertical bars correspond to number of cases per source/intersection; horizontal bars to left correspond to total number of cases per source.
Incidence & prevalence
Baseline prevalence stratified by sex
| Female |
12.38 (10.01,14.74) |
| Male |
17.08 (14.05,20.11) |
Incidence stratified by sex
| Female |
4.68 (4.12,5.24) |
| Male |
6.58 (5.85,7.31) |
Incidence stratified by age
| Ages 40-44 |
2.01 (1.13,2.89) |
| Ages 45-49 |
2.82 (1.92,3.72) |
| Ages 50-54 |
4.12 (3.12,5.13) |
| Ages 55-59 |
4.74 (3.77,5.71) |
| Ages 60-64 |
6.93 (5.92,7.94) |
| Ages 65-69 |
9.27 (7.93,10.61) |
Period prevalence
Methods
Comparison with general population
Sex-standardised prevalence from CALIBER study (Kuan et al. 2019)
| Population |
Ages 40-49 |
Ages 50-59 |
Ages 60-69 |
| UK Biobank |
18 (14,23) |
38 (33,43) |
64 (59,69) |
| CALIBER |
28 (27,30) |
56 (54,58) |
101 (98,104) |
Stratified by age and Townsend deprivation status
| Deprivation status |
Ages 40-49 |
Ages 50-59 |
Ages 60-69 |
| Least deprived |
8(3,17) |
22(15,32) |
48(39,59) |
| Low |
18(10,31) |
33(24,45) |
62(52,74) |
| Medium |
17(9,30) |
34(24,45) |
59(49,71) |
| High |
14(7,24) |
40(30,53) |
71(59,85) |
| Most deprived |
30(21,43) |
58(46,73) |
85(71,101) |
Stratified by age and country
| Country |
Ages 40-49 |
Ages 50-59 |
Ages 60-69 |
| England |
18(14,24) |
38(33,44) |
65(59,71) |
| Scotland |
16(6,32) |
42(30,59) |
67(53,85) |
| Wales |
22(9,46) |
27(15,46) |
48(33,67) |
Risk factors analysis
‘Healthy’ BMI, smoking status ‘never’, or no hypertension (absence of hypertension records) were considered as reference values.
Hazard Ratio (HR) values with P < 0.0002 were considered to show significant association with disease onset after correction for multiple-testing using the Bonferroni method
N=153513, Events=116
| Factor |
Level |
Hazard Ratio |
P value |
| BMI |
overweight |
1.85 (1.14, 2.99) |
0.0128 |
| BMI |
obese |
1.9 (1.12, 3.22) |
0.0174 |
| BMI |
underweight |
0 (0, Inf) |
0.993 |
| smoking |
previous |
0.82 (0.53, 1.27) |
0.367 |
| smoking |
current |
1.79 (1.09, 2.95) |
0.0215 |
| hypertension |
yes |
1.55 (1.01, 2.37) |
0.0432 |
Definition
| UK Biobank field id |
Description |
Code |
Value |
| 41202 |
Diagnoses - main ICD10 |
J98.1 |
Pulmonary collapse |
| 41204 |
Diagnoses - secondary ICD10 |
J98.1 |
Pulmonary collapse |
| 40001 |
Underlying (primary) cause of death: ICD10 |
J98.1 |
Pulmonary collapse |
| 40002 |
Contributory (secondary) causes of death: ICD10 |
J98.1 |
Pulmonary collapse |
| 42040 |
GP clinical event records |
23E4.11 |
O/E - collapse - lung |
| 42040 |
GP clinical event records |
H580.00 |
Pulmonary collapse with atelectasis |
| 42040 |
GP clinical event records |
H580.11 |
Atelectasis |
| 42040 |
GP clinical event records |
H580.12 |
Collapse of lung |
| 42040 |
GP clinical event records |
XE0Yc |
Pulmonary collapse with atelectasis |
| 42040 |
GP clinical event records |
XE0Yc |
Pulmonary collapse with atelectasis |
| 42040 |
GP clinical event records |
XE1hI |
O/E - collapse present |