| Name |
Seborrheic dermatitis (seb_derm) |
| Category |
Skin |
| Sex |
|
| Adult |
Yes |
| UUID |
eed0ac1a-978f-4576-ac18-11766f856f2a |
| Definition |
A dermatitis that is an inflammatory skin condition resulting in flaky, white to yellowish scales on oily areas such as the scalp or inside the ear, which is caused due to a combination of an over production of skin oil and irritation from a yeast Malassezia furfur. |
Ontologies
Key Summary Statistics
Cases from any source
| Total |
27880 |
| Female (%) |
14687 (53%) |
| Male (%) |
13193 (47%) |
Year first recorded
Cases linked in all UK Biobank sources
Cross-source concordance
Vertical bars correspond to number of cases per source/intersection; horizontal bars to left correspond to total number of cases per source.
Incidence & prevalence
Baseline prevalence stratified by sex
| Female |
601.65 (585.64,617.65) |
| Male |
650.41 (632.32,668.49) |
Incidence stratified by sex
| Female |
26.38 (24.99,27.76) |
| Male |
32.93 (31.23,34.63) |
Incidence stratified by age
| Ages 40-44 |
29.25 (25.74,32.75) |
| Ages 45-49 |
29.88 (26.85,32.91) |
| Ages 50-54 |
28.27 (25.55,31.0) |
| Ages 55-59 |
28.13 (25.67,30.59) |
| Ages 60-64 |
30.3 (28.11,32.49) |
| Ages 65-69 |
29.81 (27.32,32.29) |
Period prevalence
Methods
Comparison with general population
Sex-standardised prevalence from CALIBER study (Kuan et al. 2019)
| Population |
Ages 40-49 |
Ages 50-59 |
Ages 60-69 |
| UK Biobank |
567 (545,591) |
547 (529,565) |
575 (559,591) |
| CALIBER |
440 (435,446) |
504 (497,511) |
579 (572,587) |
Stratified by age and Townsend deprivation status
| Deprivation status |
Ages 40-49 |
Ages 50-59 |
Ages 60-69 |
| Least deprived |
603(547,663) |
536(496,577) |
623(589,660) |
| Low |
578(523,638) |
529(490,571) |
585(552,620) |
| Medium |
553(501,608) |
552(512,595) |
558(525,593) |
| High |
526(480,576) |
548(509,590) |
559(524,596) |
| Most deprived |
584(538,632) |
568(529,610) |
539(503,576) |
Stratified by age and country
| Country |
Ages 40-49 |
Ages 50-59 |
Ages 60-69 |
| England |
591(565,617) |
574(553,595) |
599(582,617) |
| Scotland |
290(244,343) |
268(234,304) |
237(209,269) |
| Wales |
780(683,886) |
751(679,829) |
839(772,910) |
Risk factors analysis
‘Healthy’ BMI, smoking status ‘never’, or no hypertension (absence of hypertension records) were considered as reference values.
Hazard Ratio (HR) values with P < 0.0002 were considered to show significant association with disease onset after correction for multiple-testing using the Bonferroni method
N=153595, Events=126
| Factor |
Level |
Hazard Ratio |
P value |
| BMI |
overweight |
0.75 (0.51, 1.1) |
0.143 |
| BMI |
obese |
0.53 (0.31, 0.88) |
0.014 |
| BMI |
underweight |
0 (0, Inf) |
0.992 |
| smoking |
previous |
1.05 (0.71, 1.56) |
0.804 |
| smoking |
current |
1.31 (0.76, 2.25) |
0.339 |
| hypertension |
yes |
1.64 (1.09, 2.47) |
0.0186 |
Definition
| UK Biobank field id |
Description |
Code |
Value |
| 20002 |
Non-cancer illness code, self-reported |
1452 |
eczema/dermatitis |
| 41202 |
Diagnoses - main ICD10 |
L21 |
Seborrhoeic dermatitis |
| 41204 |
Diagnoses - secondary ICD10 |
L21 |
Seborrhoeic dermatitis |
| 40001 |
Underlying (primary) cause of death: ICD10 |
L21 |
Seborrhoeic dermatitis |
| 40002 |
Contributory (secondary) causes of death: ICD10 |
L21 |
Seborrhoeic dermatitis |
| 42040 |
GP clinical event records |
M100.00 |
Pityriasis capitis - dandruff |
| 42040 |
GP clinical event records |
M101.00 |
Seborrhoeic dermatitis |
| 42040 |
GP clinical event records |
M101.11 |
Seborrhoeic dermatitis capitis |
| 42040 |
GP clinical event records |
M101.12 |
Seborrhoeic eczema |
| 42040 |
GP clinical event records |
M118000 |
Infantile seborrhoeic dermatitis capitis |
| 42040 |
GP clinical event records |
M118011 |
Cradle cap |
| 42040 |
GP clinical event records |
M118.00 |
Infantile seborrhoeic dermatitis |
| 42040 |
GP clinical event records |
M118z00 |
Infantile seborrhoeic dermatitis NOS |
| 42040 |
GP clinical event records |
M15y300 |
Leiner’s disease |
| 42040 |
GP clinical event records |
M165100 |
Pityriasis folliculorum |
| 42040 |
GP clinical event records |
M165200 |
Pityriasis streptogenes |
| 42040 |
GP clinical event records |
M244.11 |
Seborrhoea capitis |
| 42040 |
GP clinical event records |
M263000 |
Seborrhoea corporis |
| 42040 |
GP clinical event records |
M263100 |
Seborrhoea faciei |
| 42040 |
GP clinical event records |
M263200 |
Seborrhoea nasi |
| 42040 |
GP clinical event records |
M263300 |
Seborrhoea oleosa |
| 42040 |
GP clinical event records |
M263.00 |
Seborrhoea |
| 42040 |
GP clinical event records |
M263z00 |
Seborrhoea NOS |
| 42040 |
GP clinical event records |
Myu2000 |
[X]Other seborrhoeic dermatitis |
| 42040 |
GP clinical event records |
XE1Cq |
Folliculitis |
| 42040 |
GP clinical event records |
XE1An |
Seborrhoeic dermatitis |