| Name |
Chronic sinusitis (sinusitis) |
| Category |
Respiratory |
| Sex |
|
| Adult |
Yes |
| UUID |
07f78609-6459-4673-a408-de309d31a9e0 |
| Definition |
An inflammatory process affecting the mucous membranes of any sinus cavity. |
Ontologies
Key Summary Statistics
Cases from any source
| Total |
36360 |
| Female (%) |
22867 (63%) |
| Male (%) |
13493 (37%) |
Year first recorded
Cases linked in all UK Biobank sources
Cross-source concordance
Vertical bars correspond to number of cases per source/intersection; horizontal bars to left correspond to total number of cases per source.
Incidence & prevalence
Baseline prevalence stratified by sex
| Female |
1112.53 (1091.37,1133.69) |
| Male |
738.88 (719.7,758.07) |
Incidence stratified by sex
| Female |
61.94 (59.74,64.13) |
| Male |
41.87 (39.94,43.8) |
Incidence stratified by age
| Ages 40-44 |
50.39 (45.72,55.07) |
| Ages 45-49 |
50.72 (46.69,54.74) |
| Ages 50-54 |
52.07 (48.28,55.85) |
| Ages 55-59 |
54.86 (51.34,58.38) |
| Ages 60-64 |
54.82 (51.8,57.85) |
| Ages 65-69 |
50.11 (46.82,53.4) |
Period prevalence
Methods
Comparison with general population
Sex-standardised prevalence from CALIBER study (Kuan et al. 2019)
| Population |
Ages 40-49 |
Ages 50-59 |
Ages 60-69 |
| UK Biobank |
1222 (1189,1256) |
1266 (1240,1294) |
1268 (1245,1291) |
| CALIBER |
285 (280,289) |
371 (365,376) |
393 (387,399) |
Stratified by age and Townsend deprivation status
| Deprivation status |
Ages 40-49 |
Ages 50-59 |
Ages 60-69 |
| Least deprived |
1233(1154,1316) |
1353(1292,1417) |
1315(1264,1366) |
| Low |
1333(1250,1420) |
1286(1226,1349) |
1325(1275,1377) |
| Medium |
1224(1147,1304) |
1321(1260,1384) |
1274(1224,1325) |
| High |
1208(1138,1282) |
1239(1181,1300) |
1202(1151,1255) |
| Most deprived |
1146(1082,1213) |
1142(1087,1200) |
1205(1151,1260) |
Stratified by age and country
| Country |
Ages 40-49 |
Ages 50-59 |
Ages 60-69 |
| England |
1193(1156,1230) |
1273(1243,1303) |
1272(1246,1298) |
| Scotland |
893(812,979) |
862(802,925) |
811(758,866) |
| Wales |
2115(1955,2285) |
1885(1771,2004) |
1948(1846,2055) |
Risk factors analysis
‘Healthy’ BMI, smoking status ‘never’, or no hypertension (absence of hypertension records) were considered as reference values.
Hazard Ratio (HR) values with P < 0.0002 were considered to show significant association with disease onset after correction for multiple-testing using the Bonferroni method
N=153513, Events=116
| Factor |
Level |
Hazard Ratio |
P value |
| BMI |
overweight |
1.85 (1.14, 2.99) |
0.0128 |
| BMI |
obese |
1.9 (1.12, 3.22) |
0.0174 |
| BMI |
underweight |
0 (0, Inf) |
0.993 |
| smoking |
previous |
0.82 (0.53, 1.27) |
0.367 |
| smoking |
current |
1.79 (1.09, 2.95) |
0.0215 |
| hypertension |
yes |
1.55 (1.01, 2.37) |
0.0432 |
Definition
| UK Biobank field id |
Description |
Code |
Value |
| 20002 |
Non-cancer illness code, self-reported |
1416 |
chronic sinusitis |
| 41202 |
Diagnoses - main ICD10 |
J32 |
Chronic sinusitis |
| 41204 |
Diagnoses - secondary ICD10 |
J32 |
Chronic sinusitis |
| 40001 |
Underlying (primary) cause of death: ICD10 |
J32 |
Chronic sinusitis |
| 40002 |
Contributory (secondary) causes of death: ICD10 |
J32 |
Chronic sinusitis |
| 42040 |
GP clinical event records |
H01..11 |
Sinusitis |
| 42040 |
GP clinical event records |
H130.00 |
Chronic maxillary sinusitis |
| 42040 |
GP clinical event records |
H130.11 |
Antritis - chronic |
| 42040 |
GP clinical event records |
H130.12 |
Maxillary sinusitis |
| 42040 |
GP clinical event records |
H131.00 |
Chronic frontal sinusitis |
| 42040 |
GP clinical event records |
H131.11 |
Frontal sinusitis |
| 42040 |
GP clinical event records |
H132.00 |
Chronic ethmoidal sinusitis |
| 42040 |
GP clinical event records |
H133.00 |
Chronic sphenoidal sinusitis |
| 42040 |
GP clinical event records |
H135.00 |
Recurrent sinusitis |
| 42040 |
GP clinical event records |
H13..00 |
Chronic sinusitis |
| 42040 |
GP clinical event records |
H13..11 |
Chronic rhinosinusitis |
| 42040 |
GP clinical event records |
H13y000 |
Chronic pansinusitis |
| 42040 |
GP clinical event records |
H13y100 |
Pansinusitis |
| 42040 |
GP clinical event records |
H13y.00 |
Other chronic sinusitis |
| 42040 |
GP clinical event records |
H13yz00 |
Other chronic sinusitis NOS |
| 42040 |
GP clinical event records |
H13z.00 |
Chronic sinusitis NOS |
| 42040 |
GP clinical event records |
H17..12 |
Allergic rhinosinusitis |
| 42040 |
GP clinical event records |
Hyu2200 |
[X]Other chronic sinusitis |
| 42040 |
GP clinical event records |
XE0Y5 |
Allergic rhinitis |
| 42040 |
GP clinical event records |
XE0Y0 |
Chronic maxillary sinusitis |
| 42040 |
GP clinical event records |
XE0Xm |
Acute sinusitis |
| 42040 |
GP clinical event records |
XE0Y1 |
Chronic frontal sinusitis |