| Name |
Tinnitus (tinnitus) |
| Category |
Ear |
| Sex |
|
| Adult |
Yes |
| UUID |
a073aa2b-c18f-4caf-a4b5-bd4756bbda2d |
| Definition |
Tinnitus is the perception of noise or ringing in the ears. |
Ontologies
Key Summary Statistics
Cases from any source
| Total |
50806 |
| Female (%) |
24260 (48%) |
| Male (%) |
26546 (52%) |
Year first recorded
Cases linked in all UK Biobank sources
Cross-source concordance
Vertical bars correspond to number of cases per source/intersection; horizontal bars to left correspond to total number of cases per source.
Incidence & prevalence
Baseline prevalence stratified by sex
| Female |
925.69 (906.19,945.19) |
| Male |
1257.98 (1233.66,1282.3) |
Incidence stratified by sex
| Female |
21.74 (20.47,23.01) |
| Male |
25.48 (23.94,27.02) |
Incidence stratified by age
| Ages 40-44 |
18.17 (15.43,20.92) |
| Ages 45-49 |
18.94 (16.51,21.37) |
| Ages 50-54 |
25.96 (23.31,28.61) |
| Ages 55-59 |
24.73 (22.37,27.09) |
| Ages 60-64 |
25.61 (23.53,27.68) |
| Ages 65-69 |
23.09 (20.83,25.35) |
Period prevalence
Methods
Comparison with general population
Sex-standardised prevalence from CALIBER study (Kuan et al. 2019)
| Population |
Ages 40-49 |
Ages 50-59 |
Ages 60-69 |
| UK Biobank |
299 (282,316) |
467 (450,484) |
544 (528,559) |
| CALIBER |
284 (280,288) |
492 (486,499) |
661 (653,669) |
Stratified by age and Townsend deprivation status
| Deprivation status |
Ages 40-49 |
Ages 50-59 |
Ages 60-69 |
| Least deprived |
313(273,357) |
485(447,525) |
528(496,562) |
| Low |
284(246,326) |
455(418,494) |
533(501,566) |
| Medium |
293(256,335) |
475(438,515) |
560(527,595) |
| High |
296(261,335) |
454(419,493) |
560(525,597) |
| Most deprived |
304(271,339) |
467(431,505) |
539(503,577) |
Stratified by age and country
| Country |
Ages 40-49 |
Ages 50-59 |
Ages 60-69 |
| England |
294(276,313) |
484(465,504) |
564(546,581) |
| Scotland |
215(176,260) |
268(235,304) |
303(271,338) |
| Wales |
488(411,575) |
632(565,704) |
704(642,770) |
Risk factors analysis
‘Healthy’ BMI, smoking status ‘never’, or no hypertension (absence of hypertension records) were considered as reference values.
Hazard Ratio (HR) values with P < 0.0002 were considered to show significant association with disease onset after correction for multiple-testing using the Bonferroni method
N=153646, Events=402
| Factor |
Level |
Hazard Ratio |
P value |
| BMI |
overweight |
1.07 (0.82, 1.39) |
0.637 |
| BMI |
obese |
2.13 (1.65, 2.77) |
1.06e-08 |
| BMI |
underweight |
0 (0, Inf) |
0.986 |
| smoking |
previous |
1.48 (1.19, 1.85) |
0.000498 |
| smoking |
current |
2.47 (1.87, 3.26) |
1.43e-10 |
| hypertension |
yes |
2.21 (1.8, 2.72) |
5.76e-14 |
Definition
| UK Biobank field id |
Description |
Code |
Value |
| 4803 |
Tinnitus |
11 |
Yes, now most of the time |
| 4803 |
Tinnitus |
12 |
Yes, now alot of the time |
| 4803 |
Tinnitus |
13 |
Yes, now some of the time |
| 4803 |
Tinnitus |
14 |
Yes, but not now, but have in the past |
| 20002 |
Non-cancer illness code, self-reported |
1597 |
tinnitus / tiniitis |
| 41202 |
Diagnoses - main ICD10 |
H93.1 |
Tinnitus |
| 41204 |
Diagnoses - secondary ICD10 |
H93.1 |
Tinnitus |
| 40001 |
Underlying (primary) cause of death: ICD10 |
H93.1 |
Tinnitus |
| 40002 |
Contributory (secondary) causes of death: ICD10 |
H93.1 |
Tinnitus |
| 42040 |
GP clinical event records |
1C2..00 |
Tinnitus symptoms |
| 42040 |
GP clinical event records |
1C23.00 |
Ringing in ear |
| 42040 |
GP clinical event records |
1C24.00 |
Hissing in ear |
| 42040 |
GP clinical event records |
1C2Z.00 |
Tinnitus symptom NOS |
| 42040 |
GP clinical event records |
F583000 |
Unspecified tinnitus |
| 42040 |
GP clinical event records |
F583100 |
Subjective tinnitus |
| 42040 |
GP clinical event records |
F583200 |
Objective tinnitus |
| 42040 |
GP clinical event records |
F583.00 |
Tinnitus |
| 42040 |
GP clinical event records |
F583z00 |
Tinnitus NOS |
| 42040 |
GP clinical event records |
Z911200 |
Fit tinnitus masker |
| 42040 |
GP clinical event records |
ZEB..00 |
Observation of tinnitus |
| 42040 |
GP clinical event records |
XE17L |
Tinnitus |