Metadata
| Name | Undescended testicle (undescended_testis) |
| Category | Genitourinary |
| Sex | |
| Adult | Yes |
| UUID | 70894985-ee1e-48dd-88f0-7a2e518585e4 |
| Definition | The failure of one or both testes of a male fetus to descend from the abdomen into the scrotum during the late part of pregnancy. |
Ontologies
| Disease Ontology (DOID) | DOID_11383 |
| GWAS Catalogue | EFO_0004562 |
| MeSH | D003456 |
| SNOMED-CT | 204878001 |
| FinnGen | Q17_UNDES_TESTICLE |
Key Summary Statistics
Cases from any source
| Total | 577 |
| Female (%) | 0 (0%) |
| Male (%) | 577 (100%) |
Year first recorded
Cases linked in all UK Biobank sources
Cross-source concordance
Vertical bars correspond to number of cases per source/intersection; horizontal bars to left correspond to total number of cases per source.
Incidence & prevalence
Baseline prevalence stratified by sex
| Female | 0.0 (0.0,0.0) |
| Male | 36.68 (32.25,41.11) |
Incidence stratified by sex
| Female | 0.0 (0.0,0.0) |
| Male | 0.13 (0.03,0.23) |
Incidence stratified by age
| Ages 40-44 | 0.1 (-0.1,0.3) |
| Ages 45-49 | 0.0 (0.0,0.0) |
| Ages 50-54 | 0.06 (-0.06,0.19) |
| Ages 55-59 | 0.05 (-0.05,0.15) |
| Ages 60-64 | 0.08 (-0.03,0.18) |
| Ages 65-69 | 0.05 (-0.05,0.15) |
Period prevalence
Methods
Comparison with general population
Sex-standardised prevalence from CALIBER study (Kuan et al. 2019)
| Population | Ages 40-49 | Ages 50-59 | Ages 60-69 |
| UK Biobank | 23 (18,28) | 15 (12,19) | 12 (10,15) |
| CALIBER | 50 (47,52) | 39 (37,42) | 28 (25,30) |
Stratified by age and Townsend deprivation status
| Deprivation status | Ages 40-49 | Ages 50-59 | Ages 60-69 |
| Least deprived | 23(13,38) | 18(11,27) | 12(7,18) |
| Low | 35(22,53) | 18(11,28) | 13(8,19) |
| Medium | 28(17,44) | 13(7,22) | 13(8,20) |
| High | 17(10,29) | 13(7,21) | 12(7,19) |
| Most deprived | 16(9,26) | 15(9,23) | 11(6,18) |
Stratified by age and country
| Country | Ages 40-49 | Ages 50-59 | Ages 60-69 |
| England | 24(19,30) | 17(13,21) | 12(9,14) |
| Scotland | 21(9,39) | 13(6,24) | 20(12,31) |
| Wales | 11(2,32) | 2(0,12) | 6(2,16) |
Definition
| UK Biobank field id | Description | Code | Value |
|---|---|---|---|
| 20002 | Non-cancer illness code, self-reported | 1679 | undescended testicle |
| 41202 | Diagnoses - main ICD10 | Q53 | Undescended testicle |
| 41204 | Diagnoses - secondary ICD10 | Q53 | Undescended testicle |
| 40001 | Underlying (primary) cause of death: ICD10 | Q53 | Undescended testicle |
| 40002 | Contributory (secondary) causes of death: ICD10 | Q53 | Undescended testicle |
| 42040 | GP clinical event records | B470200 | Seminoma of undescended testis |
| 42040 | GP clinical event records | B470300 | Teratoma of undescended testis |
| 42040 | GP clinical event records | B470.00 | Malignant neoplasm of undescended testis |
| 42040 | GP clinical event records | B470z00 | Malignant neoplasm of undescended testis NOS |
| 42040 | GP clinical event records | PC50000 | Cryptorchidism, unilateral |
| 42040 | GP clinical event records | PC50100 | Cryptorchidism, bilateral |
| 42040 | GP clinical event records | PC50.00 | Cryptorchidism |
| 42040 | GP clinical event records | PC50z00 | Cryptorchidism NOS |
| 42040 | GP clinical event records | PC51.00 | Ectopic testis |
| 42040 | GP clinical event records | PC5..00 | Undescended testicle |
| 42040 | GP clinical event records | PC5z000 | Undescended testis, unilateral |
| 42040 | GP clinical event records | PC5z011 | Maldescent of testis, unilateral |
| 42040 | GP clinical event records | PC5z100 | Undescended testis, bilateral |
| 42040 | GP clinical event records | PC5z111 | Maldescent of testis, bilateral |
| 42040 | GP clinical event records | PC5z.00 | Undescended testicle NOS |
| 42040 | GP clinical event records | PC5z.12 | Maldescent of testicle |
| 42040 | GP clinical event records | XE1LF | Undescended testicle NOS |
| 42040 | GP clinical event records | XE1LG | Undescended testis, unilateral |
| 42040 | GP clinical event records | XaELM | Teratoma of undescended testis |
| 42040 | GP clinical event records | XaELJ | Seminoma of undescended testis |