| Name |
Volvulus (volvulus) |
| Category |
Digestive |
| Sex |
|
| Adult |
Yes |
| UUID |
7c0d6f8f-da03-472a-8b0f-9273262084a1 |
| Definition |
A twisting in the intestine that can cause INTESTINAL OBSTRUCTION. |
Ontologies
Key Summary Statistics
Cases from any source
| Total |
1530 |
| Female (%) |
900 (59%) |
| Male (%) |
630 (41%) |
Year first recorded
Cases linked in all UK Biobank sources
Cross-source concordance
Vertical bars correspond to number of cases per source/intersection; horizontal bars to left correspond to total number of cases per source.
Incidence & prevalence
Baseline prevalence stratified by sex
| Female |
9.19 (7.15,11.23) |
| Male |
5.88 (4.1,7.66) |
Incidence stratified by sex
| Female |
1.99 (1.62,2.35) |
| Male |
1.39 (1.05,1.72) |
Incidence stratified by age
| Ages 40-44 |
0.6 (0.12,1.09) |
| Ages 45-49 |
0.82 (0.33,1.3) |
| Ages 50-54 |
1.2 (0.66,1.74) |
| Ages 55-59 |
1.87 (1.26,2.48) |
| Ages 60-64 |
1.77 (1.26,2.28) |
| Ages 65-69 |
3.07 (2.3,3.84) |
Period prevalence
Methods
Comparison with general population
Sex-standardised prevalence from CALIBER study (Kuan et al. 2019)
| Population |
Ages 40-49 |
Ages 50-59 |
Ages 60-69 |
| UK Biobank |
9 (7,13) |
15 (12,18) |
21 (18,24) |
| CALIBER |
7 (6,7) |
12 (11,13) |
21 (20,23) |
Stratified by age and Townsend deprivation status
| Deprivation status |
Ages 40-49 |
Ages 50-59 |
Ages 60-69 |
| Least deprived |
13(6,25) |
14(9,22) |
17(12,24) |
| Low |
7(2,15) |
13(8,21) |
15(10,22) |
| Medium |
10(4,20) |
15(9,23) |
25(18,33) |
| High |
11(5,20) |
17(10,25) |
20(13,27) |
| Most deprived |
6(2,13) |
16(10,25) |
29(21,39) |
Stratified by age and country
| Country |
Ages 40-49 |
Ages 50-59 |
Ages 60-69 |
| England |
9(6,13) |
14(11,18) |
21(18,24) |
| Scotland |
9(3,22) |
18(10,29) |
27(18,39) |
| Wales |
6(1,22) |
18(8,33) |
11(4,22) |
Risk factors analysis
‘Healthy’ BMI, smoking status ‘never’, or no hypertension (absence of hypertension records) were considered as reference values.
Hazard Ratio (HR) values with P < 0.0002 were considered to show significant association with disease onset after correction for multiple-testing using the Bonferroni method
N=153646, Events=402
| Factor |
Level |
Hazard Ratio |
P value |
| BMI |
overweight |
1.07 (0.82, 1.39) |
0.637 |
| BMI |
obese |
2.13 (1.65, 2.77) |
1.06e-08 |
| BMI |
underweight |
0 (0, Inf) |
0.986 |
| smoking |
previous |
1.48 (1.19, 1.85) |
0.000498 |
| smoking |
current |
2.47 (1.87, 3.26) |
1.43e-10 |
| hypertension |
yes |
2.21 (1.8, 2.72) |
5.76e-14 |
Definition
| UK Biobank field id |
Description |
Code |
Value |
| 41202 |
Diagnoses - main ICD10 |
K56.2 |
Volvulus |
| 41204 |
Diagnoses - secondary ICD10 |
K56.2 |
Volvulus |
| 41200 |
Operative procedures - main OPCS4 |
H17.2 |
Open reduction of volvulus of caecum |
| 41200 |
Operative procedures - main OPCS4 |
H17.3 |
Open reduction of volvulus of sigmoid colon |
| 41200 |
Operative procedures - main OPCS4 |
H17.4 |
Open reduction of volvulus of colon NEC |
| 41200 |
Operative procedures - main OPCS4 |
H30.3 |
Passage of flatus tube to reduce volvulus of sigmoid colon |
| 41210 |
Operative procedures - secondary OPCS4 |
H17.2 |
H17.2 |
| 41210 |
Operative procedures - secondary OPCS4 |
H17.3 |
H17.3 |
| 41210 |
Operative procedures - secondary OPCS4 |
H17.4 |
H17.4 |
| 41210 |
Operative procedures - secondary OPCS4 |
H30.3 |
H30.3 |
| 40001 |
Underlying (primary) cause of death: ICD10 |
K56.2 |
Volvulus |
| 40002 |
Contributory (secondary) causes of death: ICD10 |
K56.2 |
Volvulus |
| 42040 |
GP clinical event records |
771D100 |
Open reduction of volvulus of caecum |
| 42040 |
GP clinical event records |
771D200 |
Open reduction of volvulus of sigmoid colon |
| 42040 |
GP clinical event records |
771D300 |
Open reduction of volvulus of colon NEC |
| 42040 |
GP clinical event records |
771R200 |
Passage of flatus tube to reduce volvulus of sigmoid colon |
| 42040 |
GP clinical event records |
J173200 |
Volvulus of duodenum |
| 42040 |
GP clinical event records |
J502100 |
Volvulus of the small bowel |
| 42040 |
GP clinical event records |
J502200 |
Volvulus of the ileocaecum |
| 42040 |
GP clinical event records |
J502300 |
Volvulus of the sigmoid colon |
| 42040 |
GP clinical event records |
J502.00 |
Volvulus |
| 42040 |
GP clinical event records |
J502.11 |
Torsion of bowel |
| 42040 |
GP clinical event records |
J502z00 |
Volvulus NOS |
| 42040 |
GP clinical event records |
XE0ap |
Volvulus |