| Name |
Ventricular tachycardia (VT) |
| Category |
Cardiovascular |
| Sex |
|
| Adult |
Yes |
| UUID |
00dc513f-406e-406b-85ec-ec863834abd5 |
| Definition |
An abnormally rapid ventricular rhythm usually in excess of 150 beats per minute. |
Ontologies
Key Summary Statistics
Cases from any source
| Total |
2129 |
| Female (%) |
532 (25%) |
| Male (%) |
1597 (75%) |
Year first recorded
Cases linked in all UK Biobank sources
Cross-source concordance
Vertical bars correspond to number of cases per source/intersection; horizontal bars to left correspond to total number of cases per source.
Incidence & prevalence
Baseline prevalence stratified by sex
| Female |
6.37 (4.67,8.06) |
| Male |
17.08 (14.05,20.11) |
Incidence stratified by sex
| Female |
1.02 (0.76,1.28) |
| Male |
3.5 (2.97,4.03) |
Incidence stratified by age
| Ages 40-44 |
0.5 (0.06,0.94) |
| Ages 45-49 |
1.19 (0.61,1.77) |
| Ages 50-54 |
1.27 (0.71,1.82) |
| Ages 55-59 |
1.82 (1.22,2.42) |
| Ages 60-64 |
2.88 (2.23,3.54) |
| Ages 65-69 |
3.67 (2.83,4.52) |
Period prevalence
Methods
Comparison with general population
Sex-standardised prevalence from CALIBER study (Kuan et al. 2019)
| Population |
Ages 40-49 |
Ages 50-59 |
Ages 60-69 |
| UK Biobank |
11 (8,15) |
17 (14,20) |
33 (29,37) |
| CALIBER |
9 (8,10) |
19 (17,20) |
39 (37,40) |
Stratified by age and Townsend deprivation status
| Deprivation status |
Ages 40-49 |
Ages 50-59 |
Ages 60-69 |
| Least deprived |
7(2,17) |
14(8,22) |
24(17,32) |
| Low |
9(3,20) |
16(9,24) |
35(27,44) |
| Medium |
14(7,26) |
18(11,27) |
28(21,37) |
| High |
11(5,21) |
14(8,23) |
40(31,51) |
| Most deprived |
13(7,22) |
22(15,32) |
39(30,51) |
Stratified by age and country
| Country |
Ages 40-49 |
Ages 50-59 |
Ages 60-69 |
| England |
11(8,15) |
17(14,21) |
34(30,39) |
| Scotland |
7(1,20) |
16(9,27) |
31(21,44) |
| Wales |
22(9,46) |
17(7,33) |
21(11,35) |
Risk factors analysis
‘Healthy’ BMI, smoking status ‘never’, or no hypertension (absence of hypertension records) were considered as reference values.
Hazard Ratio (HR) values with P < 0.0002 were considered to show significant association with disease onset after correction for multiple-testing using the Bonferroni method
N=154060, Events=218
| Factor |
Level |
Hazard Ratio |
P value |
| BMI |
overweight |
0.89 (0.65, 1.23) |
0.488 |
| BMI |
obese |
1.16 (0.82, 1.63) |
0.404 |
| BMI |
underweight |
0 (0, Inf) |
0.989 |
| smoking |
previous |
1.75 (1.31, 2.35) |
0.000182 |
| smoking |
current |
2.37 (1.58, 3.55) |
3.07e-05 |
| hypertension |
yes |
1 (0.74, 1.36) |
0.997 |
Definition
| UK Biobank field id |
Description |
Code |
Value |
| 41202 |
Diagnoses - main ICD10 |
I47.2 |
Ventricular tachycardia |
| 41204 |
Diagnoses - secondary ICD10 |
I47.2 |
Ventricular tachycardia |
| 40001 |
Underlying (primary) cause of death: ICD10 |
I47.2 |
Ventricular tachycardia |
| 40002 |
Contributory (secondary) causes of death: ICD10 |
I47.2 |
Ventricular tachycardia |
| 42040 |
GP clinical event records |
14AP.00 |
History of ventricular tachycardia |
| 42040 |
GP clinical event records |
3282.00 |
ECG: ventricular tachycardia |
| 42040 |
GP clinical event records |
G571.00 |
Paroxysmal ventricular tachycardia |
| 42040 |
GP clinical event records |
G571.11 |
Ventricular tachycardia |
| 42040 |
GP clinical event records |
XE0V4 |
Paroxysmal ventricular tachycardia |
| 42040 |
GP clinical event records |
XaLBn |
History of ventricular tachycardia |